corticosteroid responder Corticosteroid-induced glaucoma
Conditions
Interventions
- Corticosteroid-induced ocular hypertension/glaucoma
- Gene polymorphisms
- Glucocorticoids
- Ophthalmology
Sponsors
Medisch Universitair Ziekenhuis Maastricht
Eligibility
Age
18 Years to 64 Years
Inclusion criteria
Inclusion criteria: - Age > 18 year and mentally competent - Patient from the Maastricht University Medical Centre + (MUMC+), the Netherlands - Use of corticosteroids: * Patients treated with Ozurdex (an intravitreal dexamethasone implant) * Patients treated with subconjunctival Triamcinolone/ Celestone injections * Patients treated with corticosteroids after a corneal surgery * Patients treated with corticosteroids after a refractive surgery * Patients treated with corticosteroids after a cataract surgery * Patients treated with corticosteroids for macular edema * Patients exposed to corticosteroids for other diseases such as uveitis - In case of surgery, time after surgery * 3 months
Exclusion criteria
Exclusion criteria: - Age
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The primary objective is to investigate the differences in SNPs in patients with corticosteroid-induced ocular hypertension in comparison with patients exposed to corticosteroids who do not respond with an IOP increase. This can be obtained with a one-time peripheral blood sample. | — |
Secondary
| Measure | Time frame |
|---|---|
| Not applicable. | — |
Countries
The Netherlands
Outcome results
None listed