Cross-modal plasticity in the auditory cortex of pre- and postlingual deaf patients

Cross-modal plasticity in the auditory cortex of pre- and postlingual deaf patients - Cross-modal brain plasticity in deaf patients

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON47655

Enrollment

Registered

2013-06-20

Start date

2013-08-12

Completion date

Unknown

Last updated

2024-04-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Deafness hearing impairment

Interventions

None listed

Eligibility

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: In order to be eligible to participate in the complete study, a subject must meet all of the following criteria: - Age between 18 and 60 years - Normal or corrected to normal vision - Normal literacy in the Dutch or English language;Additional inclusion criteria for the three studied groups: Hearing control group - Hearing thresholds for individual frequencies tested in standard audiometry (125, 250, 500, 1000, 2000, 4000, and 8000 Hz)

Exclusion criteria

Exclusion criteria: Not fulfilling the criteria of the standard 7 Tesla fMRI inclusion list, including the presence of any type of metal in the body, tattoos on the skin and pregnancy.

Design outcomes

Primary

Measure	Time frame
The main study parameter of the fMRI experiment is the difference in Blood Oxygenation Level Dependent (BOLD) signal changes in the auditory cortex in response to visual stimuli between deaf adults and hearing controls. The main study parameter of the memory experiment is the difference in percent correct scores in spatial and temporal memory tasks between hearing and deaf adults.	—

Secondary

Measure	Time frame
The secondary parameters of the fMRI experiment are the locations and spatial organization of visually evoked Blood Oxygenation Level Dependent (BOLD) signal changes in the auditory cortex in deaf adults and the difference in BOLD signal changes in the auditory cortex in response to visual stimuli between pre- and postlingually deaf adults. The secondary parameter of the memory experiment is the difference in percent correct scores in spatial and temporal memory tasks between pre- and postlingual deaf adults.	—

Measure

Time frame

The secondary parameters of the fMRI experiment are the locations and spatial organization of visually evoked Blood Oxygenation Level Dependent (BOLD) signal changes in the auditory cortex in deaf adults and the difference in BOLD signal changes in the auditory cortex in response to visual stimuli between pre- and postlingually deaf adults. The secondary parameter of the memory experiment is the difference in percent correct scores in spatial and temporal memory tasks between pre- and postlingual deaf adults.

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Countries

Netherlands

Outcome results