Geen aandoening Attention-Deficit/Hyperactivity Disorder (ADHD)
Conditions
Interventions
None listed
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: Original study: -Dutch speaking -Right-handed -In the right age-range;Current addendum: ADHD group: - Left and right-handed - Gender: male - Fluent in Dutch - Age 14-20 - ADHD diagnosis - Normal intelligence;Matched typically developing group: - Left and right handed - Gender: male - Fluent in Dutch - Age 14-20 - No history of psychiatric disorders - Normal intelligence
Exclusion criteria
Exclusion criteria: Original study: - Current use of neurotrophic medication - Presence of chronical illness - MRI contradictions (which include metal implants, heart arrhythmia, claustrophobia) - Participants will additionally be prescreened for head trauma, learning disabilities, and history of neurological illness and/or use of psychotropic medications.;Addition current addendum: - Gender: female
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Original study: Age- and puberty related change in brain structure and function related to the construct of social-learning. MRI scans: Structural MRI will be used to gain information on gray and white matter properties (volume, density, and cortical thickness). DTI will be used to gain specific information on white matter microstructure and fibertracking. Functional MRI will be used to gain information on task-related brain activity during social learning, particularly during social observation (study 1) and during social interactions (study 2) Pubertal assessment: Participants will fill in a self-report form of pubertal maturation. Participants will also provide saliva to test for testosterone, DHEA, and estradiol levels. Current addendum: Age- and puberty related change in brain structure and function related to the construct of social-learning. MRI scans: Structural MRI will be used to gain information on gray and white matter properties (volume, density, and cortical thickness). DTI will be used to gain specific information on white matter microstructure and fibertracking. Functional MRI will be used to gain information on task-related brain activity during social learning during social observation (similar to study 1) Pubertal assessment: Participants will fill in a self-report form of pubertal maturation. Participants will also provide saliva to test for testosterone, DHEA, and estradiol levels. | — |
Secondary
| Measure | Time frame |
|---|---|
| see above | — |
Countries
Netherlands