exercise induced bronchoconstriction
Conditions
Interventions
All children are treated with Qvar 100µg twice daily for 4 weeks.
asthma
bronchial hyperresponsiveness
exercise-challenge test
Sponsors
Medisch Spectrum Twente
Eligibility
Age
2 Years to 17 Years
Inclusion criteria
Inclusion criteria: - Age between 12-18 years - Clinical history of asthma and exercise induced bronchoconstriction - Ability to perform an exercise-challenge test - Maximal FEV1 > 70% of predicted value
Exclusion criteria
Exclusion criteria: - Other pulmonary or cardiac illnesses - Use of nasal or systemic or inhalation corticosteroids, antihistamines, cromoglycates, anticholinergics or leukotriene antagonists in two weeks prior to or during the study - Use of long acting bronchodilator agents 24 hours before testing - Use of short acting bronchodilator agents 8 hours before testing - Hospitalization due to asthma exacerbation in past month - Other changes in asthma medication during treatment period - Upper or lower respiratory tract infections during treatment period - Severe EIB i.e. a fall of >=40% FEV1 in the first ECT, requiring an acute change in maintenance medication (standard care) - Insufficient knowledge of the Dutch language
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Correlation between the difference in fall in FEV1 after a single dose of Qvar and after 4 weeks of treatment with Qvar. | — |
Countries
The Netherlands
Outcome results
None listed