Medical assessment of adverse health outcomes in Dutch childhood cancer survivors; a nationwide project (DCOG LATER study) DCOG LATER substudy: Sexual function and psychosexual development in long-term childhood cancer survivors

Medical assessment of adverse health outcomes in Dutch childhood cancer survivors; a nationwide project (DCOG LATER study) DCOG LATER substudy: Sexual function and psychosexual development in long-term childhood cancer survivors - DCOG LATER - sexual function and psychosexual development

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON47606

Enrollment

6500

Registered

2015-02-02

Start date

2016-05-04

Completion date

Unknown

Last updated

2024-04-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

psychosexuele ontwikkeling sexual function and psychosexual development

Interventions

None listed

Eligibility

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: The general study design involves a nation-wide multicentre retrospective cohort study including the entire DCOG-LATER cohort of CCS according to the DCOG-LATER inclusion criteria: 1) Patients treated for childhood cancer in one of the 7 pediatric oncology centres between 1960-2001. 2) A histological verified diagnosis of malignancy covered by the ICCC3 and including long-term survivors of severe forms of Langerhans Cell Histiocytosis treated with chemotherapy and/or radiotherapy. 3) Age 0-17 years at diagnosis malignancy. 4) Survival at least 5 years from diagnosis. Additional inclusion criteria apply for the DCOG-LATER sexual function and psychosexual development study: 1) Alive at time of study 2) Age 18 years or older 3) No severe mental retardation 4) Sufficient understanding of the Dutch language to complete the questionnaires.

Exclusion criteria

Exclusion criteria: 1) Treated for childhood cancer after 2001 2) less than 5 year survival from diagnosis 3) age at time of study less than 18 years 4) living abroad at time of study 5) mental retardation 6) insufficient knowledge of dutch language to complete questionnaires

Design outcomes

Primary

Measure	Time frame
1. Prevalence of sexual dysfunctions 2. Disease and treatment related risk factors for sexual dysfunctions 3. Prevalence of distress associated with sexual dysfunction 4. Relationship factors 5. Prevalence of delayed psychosexual development 6. Disease and treatment related risk factors for delayed psychosexual development 7. Free Androgen Index (FAI, based on serum testosteron and sex hormone binding globulin levels))	—

Measure

Time frame

1. Prevalence of sexual dysfunctions 2. Disease and treatment related risk factors for sexual dysfunctions 3. Prevalence of distress associated with sexual dysfunction 4. Relationship factors 5. Prevalence of delayed psychosexual development 6. Disease and treatment related risk factors for delayed psychosexual development 7. Free Androgen Index (FAI, based on serum testosteron and sex hormone binding globulin levels))

—

Secondary

Measure	Time frame
n.a.	—

Countries

Netherlands

Outcome results