vermoeidheid tiredness weariness
Conditions
Interventions
The light intervention includes exposure to bright white light (10.000 lux at a
distance of 45 cm) for 30 minutes within the first half hour after awakening
during 3 weeks and 4 days. This can be do
cancer related fatigue
circadian rhythm
light therapy
Sponsors
Antoni van Leeuwenhoek Ziekenhuis
Eligibility
Age
18 Years to 64 Years
Inclusion criteria
Inclusion criteria: (Non-)Hodgkin lymphoma survivors (survivorship of min. 2 years) with moderate to severe fatigue symptoms; or survivors with moderate to severe restrictions on work and social activities to avoid clinical levels of fatigue.
Exclusion criteria
Exclusion criteria: Fatigue is explained by a somatic factor as defined in the guidelines of chronic fatigue syndrome of the Dutch internists association; or fatigue is explained by the treatment of (treatment for) secondary cancer in the past 12 months.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The main study parameter in this study is the change in cancer related fatigue from baseline to post-intervention and at 3 and 9 months follow-up. This will be assessed with the Multidimensional Fatigue Inventory. | — |
Secondary
| Measure | Time frame |
|---|---|
| Secundary study parameters include the following psychological variables: sleep quality, depression, anxiety, quality of life, cognitive complaints, cancer worries, fatigue catastrophizing, and self-efficacy to manage with fatigue complaints. Moreover, biological levels of cortisol and melatonin will be measured in saliva. Blood samples will be used to assess vitamin D, hsIL-6, sTNF-RII, IL-1RA, hsCRP, and genotype. | — |
Countries
The Netherlands
Outcome results
None listed