Body mass index and microcirculatory behavior in patients undergoing cardiac surgery with cardiopulmonary bypass

Body mass index and microcirculatory behavior in patients undergoing cardiac surgery with cardiopulmonary bypass - MicrObese

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON47560

Enrollment

Registered

2016-04-20

Start date

2016-05-23

Completion date

Unknown

Last updated

2024-04-23

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Perioperatieve complicaties in de doorbloeding van organen disturbances in perfusion of tissues during surgery Perioperative disturances in tissue perfusion

Interventions

None listed

Eligibility

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: * (non-aortic) cardiac surgery * Adult subjects * Informed consent * BMI * 32 kg/m2 or BMI

Exclusion criteria

Exclusion criteria: * Re-operation * Aortic surgery * Emergency operation * Diabetes mellitus type I and II

Design outcomes

Primary

Measure	Time frame
The primary endpoint is the difference in perfused vessel density before surgery and immediately after weaning from cardiopulmonary bypass.	—

Secondary

Measure	Time frame
* Patient demographics * Proportion of perfused vessels (PPV) * Perfused vessel density (PVD) * Microvascular flow index (MFI) * Perfused boundary region * Mean arterial pressure * Glucose levels * Metabolic parameters (pH, lactate, base excess, pCO2, HCO3) * Glycocalyx markers (heparan sulphate, syndecan) * Postoperative complications (ICU stay > 24 hours, mechanical ventilation > 24 hours, pneumonia, CVA/TIA, myocardial infarction, atrial fibrillation), 30-day mortality	—

Measure

Time frame

* Patient demographics * Proportion of perfused vessels (PPV) * Perfused vessel density (PVD) * Microvascular flow index (MFI) * Perfused boundary region * Mean arterial pressure * Glucose levels * Metabolic parameters (pH, lactate, base excess, pCO2, HCO3) * Glycocalyx markers (heparan sulphate, syndecan) * Postoperative complications (ICU stay > 24 hours, mechanical ventilation > 24 hours, pneumonia, CVA/TIA, myocardial infarction, atrial fibrillation), 30-day mortality

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Countries

Netherlands

Outcome results