Advanced MRI in Abdominal Aortic Aneurysms

Advanced MRI in Abdominal Aortic Aneurysms - Advanced MRI in AAA

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON47558

Enrollment

Registered

2016-07-07

Start date

2017-04-12

Completion date

Unknown

Last updated

2024-04-23

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Abdominal aortic aneurysm

Interventions

None listed

Eligibility

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: - Adult patients (* 18 years of age) - AAA with a maximal aneurysm diameter of at least 30 mm

Exclusion criteria

Exclusion criteria: - Contra-indications for MRI - Severely reduced renal function (eGFR

Design outcomes

Primary

Measure	Time frame
4D flow MRI: wall shear stress (WSS); DCE-MRI: wall permeability, expressed by the kinetic transport constant (Ktrans); T1/T2 mapping: T1/T2 relaxation time	—

Secondary

Measure	Time frame
4D flow: - Peak flow velocity inside the aneurysm - Location of peak wall shear stress - Flow velocity at aneurysm entrance - Descriptive flow patterns - Oscillatory shear index DCE-MRI: - Quantitative reverse reflux rate constant kep - Area under the curve of contrast uptake - Peak enhancement ratio - Wash-in slope - Time to peak (TTP) - Mean transit time (MTT) T1/T2 mapping: - No secondary parameters	—

Measure

Time frame

4D flow: - Peak flow velocity inside the aneurysm - Location of peak wall shear stress - Flow velocity at aneurysm entrance - Descriptive flow patterns - Oscillatory shear index DCE-MRI: - Quantitative reverse reflux rate constant kep - Area under the curve of contrast uptake - Peak enhancement ratio - Wash-in slope - Time to peak (TTP) - Mean transit time (MTT) T1/T2 mapping: - No secondary parameters

—

Countries

Netherlands

Outcome results