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Prevention of incisional hernias with prophylactic synthetic mesh placement during stoma reversal

Prevention of incisional hernias with prophylactic synthetic mesh placement during stoma reversal - Prevention of incisional hernias following stoma closure

Status
Recruiting
Phases
Phase 3
Study type
Interventional
Source
NL-OMON
Registry ID
NL-OMON47547
Enrollment
80
Registered
2016-08-16
Start date
2018-07-02
Completion date
Unknown
Last updated
2024-06-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

hernia cicatricalis incisional hernia

Interventions

One group (standard arm) receives standard stoma closure and the other group (intervention arm) will have a preventive synthetic mesh placed in addition to standard stoma closure

Sponsors

Meander Medisch Centrum
Lead Sponsor

Eligibility

Age
18 Years to 99 Years

Inclusion criteria

Inclusion criteria: Age >18 years Signed informed consent

Exclusion criteria

Exclusion criteria: Not able to sign informed consent Connective tissue disorder Intraperitoneal dialysis Immunodeficiency Use of immunosupressive medication (including high dose corticosteroids) Previous intraperitoneal mesh placement

Design outcomes

Primary

MeasureTime frame
Incisional hernia rate as detected by abdominal ultrasound at 1 year following stoma closure. An incisional hernia was defined as an opening or defect in the abdominal wall with protruding tissue trough it at the stomal incision site.

Secondary

MeasureTime frame
- Clinical diagnosis of incisional hernia at 1 year follow-up - Number of patients requiring surgical intervention for correction of a incisional hernia - Postoperative pain - 30-day mortality, cause of death - 30-day morbidity, specifically focussing on infectious complications. - 30-day re-admission and re-operation rate - Quality of life - Cost-effectiveness

Countries

Netherlands

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP)