posttraumatic stress disorder trauma
Conditions
Interventions
Half of the participants will be randomized to the stressor condition, i.e. the
socially-evaluated cold pressor task, consisting of immersing their hand into
ice cold water while being videotaped fo
Sponsors
Academisch Medisch Centrum
Eligibility
Age
18 Years to 99 Years
Inclusion criteria
Inclusion criteria: - Male sex; - Age 18-40 years;
Exclusion criteria
Exclusion criteria: - Current major medical disorder; - Current use of medications known to impact endocrine stress reactivity; - Lifetime psychiatric diagnosis; - Current significant anxiety or depressive symptoms; - Current significant PTSD symptoms;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Differences between stressor and control condition in: salivary cortisol and alpha amylase output as measured six times during the experimental paradigm and the total frequency of intrusive memories during the 7 days following the experimental paradigm. | — |
Secondary
| Measure | Time frame |
|---|---|
| - Differences between stressor and control condition in accuracy of voluntary memory and characteristics of intrusive memories related to the trauma film. - Associations between baseline glucocorticoid receptor functioning, cortisol and alpha amylase stress reactivity during the experimental paradigm and voluntary memory accuracy and intrusive memory frequency and characteristics. | — |
Countries
Netherlands
Outcome results
None listed