ASD autism
Conditions
Interventions
Autism
Multisensory integration
Sponsors
De Grote Rivieren (Dordrecht)
Eligibility
Age
12 Years to 64 Years
Inclusion criteria
Inclusion criteria: -Presence of an autism spectrum disorder (ASD; Autism, Pervasive Developmental Disorder) according to the DSM-IV-TR criteria for autism, diagnosed by a professional clinical team (added with an score of the Autism Diagnostic Observation Scale (ADOS) which is administered by certified raters) -Age between 14 and 21 years -Normal hearing and normal or corrected to normal vision -Written consent by parents or caregivers and adolescent
Exclusion criteria
Exclusion criteria: -Evidence of a serious medical, neurological or psychiatric illness (apart from ASD), seizure disorders, trauma or a use of medications affecting the nervous system -learning disabilities -mental retardation -language delays -head trauma
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The difference between individuals with ASD and healthy volunteers with respect to the underlying mechanisms of multisensory integration. In Experiment 1 the parameter is the modulation of the auditory-evoked N1 component of the event-related potential by motor-auditory prediction. In Experiment 2 the parameter is the modulation of the auditory-evoked N1/P2 components of the event-related potential by visual-auditory prediction. In Experiment 3 the parameter is the modulation of stimulus omission responses, induced by motor-auditory prediction. In Experiment 4 the parameter is the modulation of stimulus omission responses, induced by visual-auditory prediction. In Experiment 5 the parameter is the audiovisual (McGurk) mismatch negativity. In Experiment 6 the parameters are mid-latency potentials associated with the multisensory gain of speech in noise. | — |
Countries
The Netherlands
Outcome results
None listed