No conditions N.A.
Conditions
Interventions
beloningsleren
food choice
functional MRI
obese
Sponsors
Universitair Medisch Centrum Utrecht
Eligibility
Age
18 Years to 64 Years
Inclusion criteria
Inclusion criteria: • Healthy (self-reported) • Right-handed • Between 18 and 60 years old. • BMI between 18.5 and 25 kg/m2 or above 27.5 kg/m2
Exclusion criteria
Exclusion criteria: 1. Heavy moking (>10 cigarettes per day) 2. Having a history of medical or surgical events that may significantly affect the study outcome, such as metabolic or endocrine disease, or any gastro-intestinal disorder 3. Use of medication, except aspirin/paracetamol and oral contraceptives 4. MRI exclusion criteria a) Claustrophobia b) Having metal implants (i.e. pacemaker, metal joints, prostheses, etc.) or metal objects on the body which cannot be removed (i.e. piercing, hearing aid, brace, etc. c) Being pregnant.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 1. Neural activation (percentage signal change) in response to acquisition and extinction of cue-reward associations. 2. Neural activation (percentage signal change) in response to (un)healthy food choice. | — |
Secondary
| Measure | Time frame |
|---|---|
| 3. Scores on the liking of the food images and their perceived healthiness 4. Body weight at follow up. 5. Perceived temptation strength of the environment (ecological momentary assessment) 6. Food cue reactivity | — |
Countries
The Netherlands
Outcome results
None listed