MR Intracranial Vessel wall Imaging in ischemic stroke patients and TIA patients

MR Intracranial Vessel wall Imaging in ischemic stroke patients and TIA patients - IVI study

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON47383

Enrollment

150

Registered

2009-09-29

Start date

2009-12-04

Completion date

Unknown

Last updated

2024-06-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Vessel wall atheroma

Interventions

None listed

Eligibility

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: Main inclusion criteria for stroke patients and TIA patients: • 18 years or older • Male or female • Ready for MRI scanning within 3 months after onset of ischemic symptoms;Additional inclusion criteria for stroke patients: • Ischemic symptoms conform PACI/TACI (Partial/Total Anterior Circulation Infarct);Additional inclusion criteria for TIA patients: • Transient ischemic symptoms (

Exclusion criteria

Exclusion criteria: • Patients with a stroke secondary to surgical / interventional procedures • Allergic reaction to gadolinium • Patients with impaired renal function (severe renal insufficiency, GFR

Design outcomes

Primary

Measure	Time frame
Our main study parameter is the presence or absence of intracranial atherosclerosis in one (or more) arteries of the anterior cerebral circulation in the aforementioned groups.	—

Secondary

Measure	Time frame
Our secondary study parameters are signal characteristics of the intracranial vessel wall atheroma, specifically unstable atheroma, on multiple MRI sequences, and assessment of clinical consequences of intracranial atherosclerosis by evaluation of standard brain imaging. Furthermore we would like to evaluate the accuracy and utility of the short vessel wall sequence compared to the current more time-consuming vessel wall sequence. We will assess whether this short vessel wall sequence has the potential to replace the longer vessel wall sequence in future.	—

Measure

Time frame

Our secondary study parameters are signal characteristics of the intracranial vessel wall atheroma, specifically unstable atheroma, on multiple MRI sequences, and assessment of clinical consequences of intracranial atherosclerosis by evaluation of standard brain imaging. Furthermore we would like to evaluate the accuracy and utility of the short vessel wall sequence compared to the current more time-consuming vessel wall sequence. We will assess whether this short vessel wall sequence has the potential to replace the longer vessel wall sequence in future.

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Countries

Netherlands

Outcome results