Inhibitory sensory-motor links in the human brain

Inhibitory sensory-motor links in the human brain - Inhibitory sensory-motor links in the human brain

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

NL-OMON

Registry ID

NL-OMON47324

Enrollment

Registered

2013-06-11

Start date

2013-11-08

Completion date

Unknown

Last updated

2024-04-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Geen aandoening maar onderzoek richt zich op inhibitiemechanismen bij gezonde deelnemers but rather focuses on a fundamental question regarding mechanisms of inhibition. The aim of the current research does not pertain to a specific pathology

Interventions

None listed

Eligibility

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: between 18-45 years old.

Exclusion criteria

Exclusion criteria: (History of) epilepsy psychopathology

Design outcomes

Primary

Measure	Time frame
The following electrophysiological correlates of inhibition are of interest: Stop N1: This is the modulation of the N1 (electrophysiological negative peak) by stopping success. Or more specifically, the degree to which the N1 is larger for successful as opposed to failed stops. This modulation is interpreted as characterizing the potentiated inhibitory link between sensory (auditory or visual cortex, depending on the specific SST variant) and motor cortex (under control of a tonically active right frontal cortex). Stop N2: This is the modulation of the N2 by stopping success. More specifically, the degree to which the N2 is larger for successful as opposed to failed stops. This modulation is interpreted as characterizing inhibition related activity within the right frontal cortex.	—

Measure

Time frame

The following electrophysiological correlates of inhibition are of interest: Stop N1: This is the modulation of the N1 (electrophysiological negative peak) by stopping success. Or more specifically, the degree to which the N1 is larger for successful as opposed to failed stops. This modulation is interpreted as characterizing the potentiated inhibitory link between sensory (auditory or visual cortex, depending on the specific SST variant) and motor cortex (under control of a tonically active right frontal cortex). Stop N2: This is the modulation of the N2 by stopping success. More specifically, the degree to which the N2 is larger for successful as opposed to failed stops. This modulation is interpreted as characterizing inhibition related activity within the right frontal cortex.

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Countries

Netherlands

Outcome results