Spondyloarthritis
Conditions
Interventions
None listed
Sponsors
Vrije Universiteit Medisch Centrum
Eligibility
Age
18 Years to 99 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria: -* diagnosis of axial or peripheral spondyloarthritis, according to the: o the modified New York criteria OR o the ESSG criteria OR o the ASAS classification criteria, including axial as well as peripheral SpA * signed informed consent
Exclusion criteria
Exclusion criteria: Unable to understand the study aims and methods;Remark: For patients initiating a biological, a treatment selection in daily clinical practice on contra-indications described in the Dutch national guidelines for initiation of a biological treatment, were taken into consideration, especially considering females. An exception is made for treatment with certoluzimab, which can be continued during late gestation and during breastfeeding
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Parameters that were collected during the regular visits at the outpatient clinic are: (changes in) disease activity (BASDAI and ASDAS and inflammatory markers (CRP- and ESR-levels), frequency of adverse events and drug adherence and response during biological treatment and disease progression (radiographic changes on X-rays and /or MRI, and change of classification from nr-axial SpA to AS). In addition, parameters concerning changes in function (BASFI), in range of motion (BASMI), occurrence of extra-articular manifestations and comorbidities and BMD change (DEXA scans) were collected during the regular visits. | — |
Secondary
| Measure | Time frame |
|---|---|
| n.a. | — |
Countries
Netherlands
Outcome results
None listed