neuropathic pain syndrome
Conditions
Interventions
local treatment with either ketamine 10% or amitriptyline 10% cream or placebo
neuropathic
pain-relievingcream
Pilot-study
Sponsors
Westfries Gasthuis
Eligibility
Age
18 Years to 64 Years
Inclusion criteria
Inclusion criteria: - peripheral neuropathic pain (DOT: 130) - >= 18 years old, competent - >= 5 and
Exclusion criteria
Exclusion criteria: - pregnancy or planned pregnancy during study period - open wounds on the place of the neuropatic pain - current use of topical analgetic - presence of other painsyndromes, like the widespread painsyndrome - presence of serious psychological or psyciatric morbidity - addiction on intoxicans - insufficient control of the Dutch language - use of ketamine and amitriptyline - known allergy of the studymedication (active substance en additives)
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Difference between active and placebo cream pain score on Numerical Rating Scale | — |
Secondary
| Measure | Time frame |
|---|---|
| Feasibility of a randomised, doubleblind, placebo-controlled, cross-over study with the folowing questions: effectiveness on the other rating scales, percentage patients responding and will be included after the testing phase; comprehensibility and completeness of questionnaires, percentage drop-outs, side effects, logistics and randomization process, tolerance and safety of the creams . | — |
Countries
The Netherlands
Outcome results
None listed