EEG in patients with acute stroke: detection of secondary deterioration and outcome prediction

EEG in patients with acute stroke: detection of secondary deterioration and outcome prediction - EEG in acute stroke

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON47253

Enrollment

Registered

2014-09-23

Start date

2014-11-17

Completion date

Unknown

Last updated

2024-04-23

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

cerebrovascular accident ischemic stroke

Interventions

None listed

Eligibility

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: -Age 18 years or older -Diagnosis of acute stroke -Possibility to start EEG monitoring within 48 hours from symptom onset -Admission to the stroke unit -Neurological deficit with a National Institutes of Health Stroke Scale (NIHSS) score *2 -Degree of disability before stroke on modified Rankin Scale (mRS) score

Exclusion criteria

Exclusion criteria: - Any progressive brain illness, such as a brain tumor or neurodegenerative disease -Expectation that the patient will die due to the stroke

Design outcomes

Primary

Measure	Time frame
The main study parameters are (1) neurological deterioration during hospital admission (=primary outcome measure), and (2) incidence of EEG patterns that indicate cortical spreading depressions, epileptiform activity, infraslow activity, of disturbed functional connectivity in the contralesional hemisphere.	—

Secondary

Measure	Time frame
Secondary outcome measures will be functional outcome defined as the score on the mRS, the Barthel index, and major depressive disorder 6-8 weeks after discharge.	—

Countries

Netherlands

Outcome results