Skip to content

Cognitive impairment in Multiple Sclerosis: Investigating the temporal dynamics of functional reorganization, cognition, and the susceptibility to change after cognitive rehabilitation

Cognitive impairment in Multiple Sclerosis: Investigating the temporal dynamics of functional reorganization, cognition, and the susceptibility to change after cognitive rehabilitation - Cognitive rehabilitation in MS

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
NL-OMON
Registry ID
NL-OMON47185
Enrollment
110
Registered
2014-12-11
Start date
2015-02-13
Completion date
Unknown
Last updated
2024-04-23

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

MS Multiple Sclerose

Interventions

A computer-based attention training will be provided for 7 weeks (once a week, 45 minutes per session) in the experimental group. The control group (waiting list) will not engage in any cognitive re

Sponsors

Vrije Universiteit Medisch Centrum
Lead Sponsor

Eligibility

Age
18 Years to 99 Years

Inclusion criteria

Inclusion criteria: - Clinically definite MS - Age between 18-68 years - Meet safety criteria to undergo MRI examination - Sufficient motor skills

Exclusion criteria

Exclusion criteria: - History of drug abuse - Neurological diseases (for paitents: other than MS) - Psychiatric diseases - For patients: relapse free and steroid treatment free for at least 4 weeks prior to examination -For patients: not allowed to participate in other intervention studies while they are participating in this study

Design outcomes

Primary

MeasureTime frame
1) Changes in brain activation and networks in relationship with cognitive decline (5 year follow-up) 2) Changes in cognitive function after attention training 3) Changes in brain activation and networks in relationship after attention training

Secondary

MeasureTime frame
- The effect of cognitive rehabilitation on subjective cognitive functioning

Countries

Netherlands

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP)