coagulation disorder Inherited bleeding disorder
Conditions
Interventions
None listed
Sponsors
Academisch Medisch Centrum
Eligibility
Age
2 Years to 17 Years
Inclusion criteria
Inclusion criteria: 1. Age 0-18 years 2. Presenting with (1) the history, signs and symptoms of bleeding, and/or (2) abberant laboratory blood parameters and/or (3) a diagnosis of a bleeding disorder in relatives
Exclusion criteria
Exclusion criteria: 1. Patients with a previous diagnosis of an inherited bleeding disorder 2. Patients with a known, acquired cause of bleeding (ie. renal or liver disease, use of medication that is known to cause an increased bleeding tendency)
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The main study outcome is the diagnostic accuracy of a newly developed pediatric BAT. This will be analysed by calculating the area under the Receiver operating characteristic curve (ROC) . | — |
Secondary
| Measure | Time frame |
|---|---|
| Linear regression will be used to model the association of bleeding score with age, sex and type of bleeding disorder in an multivariatble model | — |
Countries
Netherlands
Outcome results
None listed