Pijn experience en cognition in Williams, Prader-Willi en Fragiele-X syndromes

Pijn experience en cognition in Williams, Prader-Willi en Fragiele-X syndromes - Pijn bij Williams, Prader-Willi en Fragiele-X syndromen

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON47146

Enrollment

200

Registered

2016-12-15

Start date

2016-12-24

Completion date

Unknown

Last updated

2024-04-23

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

chromosome 15 en X chromosome Prader-Willi syndrome en Fragiele-X syndromes

Interventions

None listed

Eligibility

Age

2 Years to 99 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria of the clinical groups are: - Wiliams, Prader-Willi, or Fragile-X syndrome according to genetic assessment - Adult age (18 years and older) - Capable of speaking;Inclusion criteria of the control groups are: - Control group matched on calendar age: adults (18 years and older) - Control group matched on mental age: children 2-17 years - Participants in both control groups are capable to speak Dutch

Exclusion criteria

Exclusion criteria: Exclusion criteria of the clinical groups are: - Severe level of intellectual disability - Comorbid psychiatric disorder due to which the test session is not possible - Visual or auditory impairments due to which the test session is not possible - Advanced stage of dementia due to which the test session is not possible;Exclusion criteria of the control groups are: - Indication of 'special education': attending such education in present or past - Diagnosis of a genetic abnormality - Diagnosis of a neurological condition - Diagnosis of a disorder in speaking or understanding language - Diagnosis of emotional disorders (such as depression, bipolar disorder, anxiety disorder), attention deficit or behavioural disorder (such as ADD, ADHD, ODD, CD) autism or autism spectrum disorder (such as PDD-NOS), or mental disorders (such as borderline, schizophrenia, OCD, psychoses) - Visual or auditory impairments due to which the test session is not possible - Use of antipsychotic, anticonvulsant, or antidepressive medication - Use of a wheel chair (due to movements during the test assessment)

Design outcomes

Primary

Measure	Time frame
The primary parameters are: 1) the difference in the pain characteristics between clinical groups and between clinical groups and control groups; and 2) the relationship between pain experience and cognitive function in the clinical groups.	—

Secondary

Measure	Time frame
Not applicable.	—

Countries

Netherlands

Outcome results