burn wound infection wound contamination
Conditions
Interventions
Volunteers will be treated once with cold gas plasma.
Sponsors
Vereniging Samenwerkende Brandwondencentra Nederland
Eligibility
Age
18 Years to 99 Years
Inclusion criteria
Inclusion criteria: -18 years or older, -have completed informed consent forms; -able and willing to comply with the research protocol; -no language barrier
Exclusion criteria
Exclusion criteria: - Atopic dermatitis or other skin disease - Implanted electrical medical devices such cardiac pacemakers - Pregnant or lactating women - Patients with infected wounds. - Life-threatening cardiac conductivity abnormality - Active malignancy - Women of childbearing age not using contraceptive measures
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Safety of plasma treatment: occurance of SAE and pain scores will be recorded. Plasma treatment is considere safe when in * 10% moderate SAE due to the treatment. Pain: a VAT score above 2 is considered as a cutoff value for SAE. | — |
Secondary
| Measure | Time frame |
|---|---|
| The effect of plasma treatment on TEWL, local skin temperature, colorimetry and bacterial load will be determined. | — |
Countries
Netherlands
Outcome results
None listed