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The changing over time of ascorbic acid after chemotherapy and the correlation between ascorbic acid and the recovery of the immune cells after chemotherapy in patients receiving intensive clinical chemotherapy for acute leukemia and high dose chemotherapy with autologous stem cell rescue and in outpatients receiving relatively mild chemotherapy for lung cancer and colon cancer.

The changing over time of ascorbic acid after chemotherapy and the correlation between ascorbic acid and the recovery of the immune cells after chemotherapy in patients receiving intensive clinical chemotherapy for acute leukemia and high dose chemotherapy with autologous stem cell rescue and in outpatients receiving relatively mild chemotherapy for lung cancer and colon cancer. - Changing over time of ascorbic acid after chemotherapy

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
NL-OMON
Registry ID
NL-OMON47053
Enrollment
95
Registered
2015-09-21
Start date
2016-09-12
Completion date
Unknown
Last updated
2024-07-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

malignancies cancer

Interventions

None listed

Sponsors

Medisch Universitair Ziekenhuis Maastricht
Lead Sponsor

Eligibility

Age
18 Years to 99 Years

Inclusion criteria

Inclusion criteria: - 18 years or older - written informed consent - Require chemotherapy and will start this treatment in less than 1 month after registration for any of the following diseases: • Acute leukemia or high risk myelodysplasia (RAEB2) • Hematological disease requiring autologous stem cell transplantation after chemotherapy - Or family member of a participant (without malignancy or chemotherapy)

Exclusion criteria

Exclusion criteria: - recent (

Design outcomes

Primary

MeasureTime frame
Influence of chemotherapy on AA levels in plasma and in leukocytes.

Secondary

MeasureTime frame
Relation between AA levels and immune cells.

Countries

Netherlands

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP)