autisme spectrum stoornis en synesthesie (veranderde waarneming) ASD
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: Autism group: ADOS or ADI-verified ASD diagnosis according to DSM-5, age 4-5 years old, Performance IQ>85 Healthy controls: 4 or 5 years old, starting Group 2 of primary school in same calendar year Healthy controls at familial risk for synaesthesia: as control group but at least one parent has a form of synaesthesia as verified by a consistency test.
Exclusion criteria
Exclusion criteria: visual impairments, seizure disorders, history of serious head injury, claustrophobia, psychotropic medication, genetic syndromes that are known to cause autism spectrum disorder (e.g. Fragile X, Angelman syndrome)
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The main dependent variables are: * Time locked voltage changes (*V) at different electrode sites (EEG), i.e. the ratio between the N1/ P1 components at occipital sites for achromatic visual stimuli | — |
Secondary
| Measure | Time frame |
|---|---|
| - Time locked voltage changes (*V) at different electrode sites (EEG) for chromatic visual stimuli - Power changes (*V2) at different electrode sites (EEG) - Percentage correct hits in a prospective memory experiment (distractor task) - Reading proficiency scores on a passive and an active reading task (% correct) - Synaesthesia scores (% of consistent colour associations across sessions). - Control measurements: Social Responsiveness Scale, Sensory Profile, IQ tests. | — |
Countries
The Netherlands