Localizing the eloquent cortex in children with epilepsy: Development and validation of a child-friendly fMRI protocol

Localizing the eloquent cortex in children with epilepsy: Development and validation of a child-friendly fMRI protocol - Localizing the eloquent cortex in children with epilepsy

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON46983

Enrollment

Registered

2016-07-20

Start date

2016-12-27

Completion date

Unknown

Last updated

2025-08-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

epilepsy

Interventions

None listed

Eligibility

Age

2 Years to 11 Years

Inclusion criteria

Inclusion criteria: Pilot phase and phase 2: - Healthy subjects (m/f) - Age 6-10;Phase 3: - Epilepsy patients (m/f) scheduled for epilepsy surgery - Age 6-10 or older with a mental age equivalent to this age range. The patients neurologist/neuropsychologist will decide whether older patients meet this criteria by evaluating the results of the patients neuropsychological assessment which includes IQ testing with for example the WPPSI-III-NL or WISC-III-NL. These tests are part of the clinical examination procedures and are performed by all epileptic patients who might require surgery

Exclusion criteria

Exclusion criteria: - Metal objects in the body that are not MRI compatible - Anxiety in the scanner (evaluated by parent/caretaker, or after practice in mock scanner)

Design outcomes

Primary

Measure	Time frame
- Similarity amongst fMRI activation patterns of healthy controls - Match between fMRI activation pattern and standard diagnostic results in epilepsy patients	—

Secondary

Measure	Time frame
NVT	—

Countries

Netherlands

Outcome results