Examining the longitudinal associations between negative peer experiences on adolescent inflammation

Examining the longitudinal associations between negative peer experiences on adolescent inflammation - Peer experiences and adolescent inflammation

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON46973

Enrollment

250

Registered

2016-06-30

Start date

2016-11-28

Completion date

Unknown

Last updated

2024-04-23

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Heightened inflammation Not applicable

Interventions

None listed

Eligibility

Age

12 Years to 17 Years

Inclusion criteria

Inclusion criteria: Adolescents enrolled in the first year of high school.

Exclusion criteria

Exclusion criteria: Autoimmune diseases and/or hyperactive thyroid

Design outcomes

Primary

Measure	Time frame
High sensitivity C-reactive protein (hsCRP), an index of systemic inflammation, will be assessed at each wave of data collection using dried blood spots. The main study parameter is changes in hsCRP over time as a function of exposure to negative peer experiences (e.g., peer victimization, peer rejection) across adolescents with different levels of interpersonal sensitivity.	—

Secondary

Measure	Time frame
This project also offers the opportunity to address a number of relevant secondary objectives, concerning a) the link between inflammation and depression, b) developmental transactional effects across peer adversity, inflammation and internalizing symptoms and c) the relationship between self-conscious emotion and inflammation. Therefore, this study will include internalizing symptoms (i.e., depressive symptoms, anxiety, loneliness), self-conscious emotion and emotion regulation as secondary parameters.	—

Measure

Time frame

This project also offers the opportunity to address a number of relevant secondary objectives, concerning a) the link between inflammation and depression, b) developmental transactional effects across peer adversity, inflammation and internalizing symptoms and c) the relationship between self-conscious emotion and inflammation. Therefore, this study will include internalizing symptoms (i.e., depressive symptoms, anxiety, loneliness), self-conscious emotion and emotion regulation as secondary parameters.

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Countries

Netherlands

Outcome results