Ehlers-Danlos (hypermobility type) Hypermobility Syndrome
Conditions
Interventions
Gait analysis
Generalized joint hypermobility
Hypermobility Syndrome
Musculoskeletal pain
Sponsors
Academisch Medisch Centrum
Eligibility
Age
12 Years to 64 Years
Inclusion criteria
Inclusion criteria: Inclusion will be based on one of the following diagnoses:;Hypermobility Syndrome: according to the Brighton criteria Ehlers Danlos (hypermobility type): Villefranche criteria Generalized Joint Hypermobility: Beighton score >4
Exclusion criteria
Exclusion criteria: Primary exclusion criteria encompass the presence of other heritable disorders of connective tissue (HDCT) like Ehlers-Danlos (other than the hypermobile type), Marfan syndrome or osteogenesis imperfecta. If genetic screening rules out HDCT*s, the participant is again eligible for inclusion in the study.;Secondary exclusion criteria encompass: -A history of surgery is present on the extremities, spine or thorax that could interfere with walking, or with arm/hand function related activities. -Any conditions that render the participant too unfit to be tested (such as pulmonary and/or cardiac disorders) -Any conditions that render the participant unable to understand or adhere to the protocol (such as cognitive, social, visual and/or language problems, or hand problems, that render the patient unfit to fill-in the questionnaires).
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The primary outcomes will be set at the amount of activity impairment. | — |
Secondary
| Measure | Time frame |
|---|---|
| Secondary outcomes will entail potential contributing factors for activity impairment in terms of Musculoskeletal complaints (pain and fatigue), physical factors (Joint biomechanics, muscle power, proprioception) and psychological factors (psychological comorbidity and parental factors). | — |
Countries
The Netherlands
Outcome results
None listed