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Prediciton of renal response to intravenous fluid administration by passive leg raising and stroke volume variation in critically ill patients.

Prediciton of renal response to intravenous fluid administration by passive leg raising and stroke volume variation in critically ill patients. - Renal fluid responsiveness

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
NL-OMON
Registry ID
NL-OMON46898
Enrollment
35
Registered
2015-02-05
Start date
2015-04-24
Completion date
Unknown
Last updated
2024-04-23

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Vloeistofovervulling Acute kidney injury/acute tubulus necrosis and fluid overload

Interventions

None listed

Sponsors

Medisch Centrum Alkmaar
Lead Sponsor

Eligibility

Age
18 Years to 99 Years

Inclusion criteria

Inclusion criteria: - Mechanically ventilated patients of both gender - Age 21 years and under 80 years of age - admitted to the intensive care unit (ICU) with oliguria (

Exclusion criteria

Exclusion criteria: - medical grounds: the physician requires to deviate from current protocol to adequately treat other life threatening events. - ethical grounds: e.g. pre-terminal illness - Loss of blood >100 ml per hour - relevant alterations in inotropic or vasopressor medication. - Use of clinically relevant diuretics (furosemide, bumetanide, hydrochloorthiazide during the research protocol) - a known medical history of significant heart failure requiring daily administration of high dose diuretics. - pulmonary edema. - pregnancy - practical drawbacks

Design outcomes

Primary

MeasureTime frame
The study parameters are: SVV, stroke volume (SV) and cardiac output (CO), static haemodynamic parameters including SvO2, lactate, diuresis and urinary indices.

Secondary

MeasureTime frame
For the substudy fluid in the lungs will be assessed by looking at artefacts with lung ultrasound.

Countries

Netherlands

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP)