Vloeistofovervulling Acute kidney injury/acute tubulus necrosis and fluid overload
Conditions
Interventions
None listed
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: - Mechanically ventilated patients of both gender - Age 21 years and under 80 years of age - admitted to the intensive care unit (ICU) with oliguria (
Exclusion criteria
Exclusion criteria: - medical grounds: the physician requires to deviate from current protocol to adequately treat other life threatening events. - ethical grounds: e.g. pre-terminal illness - Loss of blood >100 ml per hour - relevant alterations in inotropic or vasopressor medication. - Use of clinically relevant diuretics (furosemide, bumetanide, hydrochloorthiazide during the research protocol) - a known medical history of significant heart failure requiring daily administration of high dose diuretics. - pulmonary edema. - pregnancy - practical drawbacks
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The study parameters are: SVV, stroke volume (SV) and cardiac output (CO), static haemodynamic parameters including SvO2, lactate, diuresis and urinary indices. | — |
Secondary
| Measure | Time frame |
|---|---|
| For the substudy fluid in the lungs will be assessed by looking at artefacts with lung ultrasound. | — |
Countries
Netherlands