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Detailed Speech & Language Phenotyping in SATB2-Associated syndrome

Detailed Speech & Language Phenotyping in SATB2-Associated syndrome - SPELA-SAS

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
NL-OMON
Registry ID
NL-OMON46826
Enrollment
25
Registered
2018-09-12
Start date
2019-04-11
Completion date
Unknown
Last updated
2024-04-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

intellectual disability SATB2-associated syndrome

Interventions

None listed

Sponsors

Radboud Universitair Medisch Centrum
Lead Sponsor

Eligibility

Age
2 Years to 99 Years

Inclusion criteria

Inclusion criteria: - A molecular diagnosis of SATB2-associated syndrome (SAS) - At least two years old at the time of testing - Raised in Dutch-speaking family

Exclusion criteria

Exclusion criteria: - the presence of another gene disruption/molecular diagnosis that is likely to contribute to the neurodevelopmental phenotype

Design outcomes

Primary

MeasureTime frame
A common speech and language phenotype (*deep phenotype*) for patients with SAS, with a detailed description on three different domains: oral motor skills, speech and language. In addition to that, a non-verbal and/or performance IQ score.

Countries

Netherlands

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP)