incomplete dwarslaesies Multiple Sclerosis (MS) Spinal Cord Injury (SCI)
Conditions
Interventions
None listed
Sponsors
Libra Revalidatie & Audiologie
Eligibility
Age
18 Years to 99 Years
Inclusion criteria
Inclusion criteria: Multiple Sclerosis (MS) -EDSS * 6.5 (needs mainly support on two sides or support tools to walk 20 meters (EDSS
Exclusion criteria
Exclusion criteria: - Contra-indications to perform a progressive cardiopulmonary exercise test (CPET) (Lausanne protocol ); - Abnormalities detected during the CPET which contra-indicate high intensity physical activities; - Pregnancy; - Unable to complete the full intervention based on time investment; - Essential changes in medication during the intervention period (e.g. disease-modifying drugs in MS); - Use of beta-blockers; - MS Relapse during the intervention period; - Malignant tumor as cause of SCI; - Any premorbid (before diagnosis of MS/SCI) progressive neuromuscular or brain disease.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Main study parameters: Primary parameters are: - aerobic capacity (progressive cardiopulmonary exercise test) - physical performance (Stair Climb Test, Progressive Isoinertial Lifting Evaluation, Sit To Stand test, Timed-up-and-Go test, 6 minute walk test maximal distance). | — |
Secondary
| Measure | Time frame |
|---|---|
| Secondary parameters are: - maximal muscle strength (1RM handgrip, 1RM legpress), - walking efficiency (6 minute walk test at comfortable speed), - fatigue (Fatigue Severity Scale (FSS), - quality of life (Short Form (36) Health Survey (SF-36), and Multiple Sclerosis Impact Scale (MSIS-29)), - feasibility of the program (questionnaire developed for this study). * | — |
Countries
Netherlands
Outcome results
None listed