Hemodynamiek. Intraoperatief hypotension low blood pressure
Conditions
Interventions
We look at the effect of introduction of a protocol (based on FloTracIQ) with
blood pressure targets and predictive analytics (HPI) to reduce the time
weighted average (TWA) spent in hypotension dur
Anesthesiology
Hypotension
Intraoperative monitoring
Machine learning
Sponsors
Academisch Medisch Centrum Amsterdam
Eligibility
Age
18 Years to 64 Years
Inclusion criteria
Inclusion criteria: * Aged 18 years or older * Planned for elective non-cardiac non-day surgery with an expected duration of more than 2 hours * Planned to receive general anaesthesia * Planned to receive an arterial line during surgery * Aim for MAP of 65 mmHg during surgery * Being able to give written informed consent prior to surgery
Exclusion criteria
Exclusion criteria: * Aim for MAP other than 65 mmHg at discretion treating physician * Significant hypotension before surgery defined as a MAP
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Phase A: Prospective data collection Main study parameters/endpoints * Time weighted average spent in hypotension (defined as MAP100 mmHg) during surgery? * Incidence of hypertension (defined as MAP >100 mmHg) during surgery? * TWA spent in hypertension (defined as MAP>100 mmHg) during surgery? * Hemodynamic parameters, measured beat tot beat (CO, SV, SVV, SVR, elastance, dP/dT) Phase B: RCT Main study parameters/endpoints We compare a group with access to HPI and access to FlotracIQ parameters (CO, SV, SVR, SVV, dynamic elastance, dP/dT, see appendix II) to a group treated according to institutional standard care. * Time weighted average spent in hypotension (defined as MAP100 mmHg) during and after surgery? * Incidence of hypertension (defined as MAP >100 mmHg) during and after surgery? * TWA spent in hypertension (defined as MAP>100 mmHg) during and after surgery? | — |
Secondary
| Measure | Time frame |
|---|---|
| See primary study parameters | — |
Countries
The Netherlands
Outcome results
None listed