chronic bronchitis Emphysema
Conditions
Interventions
Patients participating in a routine 40-session rehabilitation program at CIRO+
will be randomized to the use of nasal high flow (NHF) oxygen supplementation
during both exercise training and night t
Sponsors
CIRO+ Horn
Eligibility
Age
18 Years to 99 Years
Inclusion criteria
Inclusion criteria: - - Patients with COPD with hypoxia which at least demand 1 liter oxygen/min during baseline. - Clinical stable on the basis of clinical picture by the chest physician. - Documented desaturation during exercise, which demands at least 2 liters oxygen/min to correct. - Permission for voluntary participation. Patient will be asked during the start of their rehabilitation program and have to sign an informed consent. Patients have the right to withdraw from the study without any negative consequences on their rehabilitation. - Attending the regular rehabilitation program in CIRO+.
Exclusion criteria
Exclusion criteria: - Lack of motivation for voluntary participation in the present study. - Not capable to understand the instruction of the NHF oxygen delivery system - Outpatient pulmonary rehabilitation program in a hospital which is part of the CIRO network. - Not capable to perform cycle tests, walk tests and/or endurance training on a cycle ergometer and treadmill.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The main study parameter is the increase in cycle endurance time after completion of the PR program and 6 months after completion of the PR program. | — |
Secondary
| Measure | Time frame |
|---|---|
| Secondary study parameters are changes in 6-min walking distance (6MWD), increase in training intensity, oxygen saturation, heart rate, Borg scores for dyspnoea and fatigue, lung function, health status and the number of exacerbations and hospitalizations. Long term outcome measures for the follow-up period are lung function, cycle endurance time, daily symptoms and the number of exacerbations and hospitalizations. | — |
Countries
Netherlands
Outcome results
None listed