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Head in the Game - a study on long-term effects of playing elite football on brain structure and function

Head in the Game - a study on long-term effects of playing elite football on brain structure and function - Head in the Game

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
NL-OMON
Registry ID
NL-OMON46652
Enrollment
80
Registered
2018-06-20
Start date
2017-10-01
Completion date
Unknown
Last updated
2024-02-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

brain damage

Interventions

brain function
brain structure
elite atheletes

Sponsors

Fédération Internationale de Fotoball Association (FIFA)
Lead Sponsor

Eligibility

Age
18 Years to 64 Years

Inclusion criteria

Inclusion criteria: two groups of atheltes will be included in this study:;50 football players - female, aged 30-50 years - played at least 5 mathces in a first league club team or the national team - retired from elite football over 2 years ago (no first league or international matches);30 elite athletes from non-contact sports - age, gender and handedness matched - former elite athlete (over 5 competitions at national or international level) in a non-contact sport or anthoer sport with a low risk of head injury - Retired from elite sports over 2 years ago (no competition on national or international level)

Exclusion criteria

Exclusion criteria: Football players * Previous non-football-related severe head injury diagnosed or treated by a physician * Symptomatic mental disorder (e.g. depression or schizophrenia). * Symptomatic chronic disease (i.e. cancer, diabetes, cardiovascular disease) except osteoarthrosis/-arthritis and medically controlled hypertension. * MRI contra-indications (specified below).;Elite athletes * Previous or current regular participation (* once a week for *1 year) in football, or other sports with high risk of head injury. * Previous severe head injury diagnosed or treated by a physician. * Symptomatic mental disorder (e.g. depression, schizophrenia). * Symptomatic chronic disease (i.e. cancer, diabetes, cardiovascular disease, dementia), except osteoarthrosis/-arthritis and medically controlled hypertension. * MRI contra-indications (specified below).;MRI Contraindication * Pregnancy (even though there is no evidence of adverse effects). * Metal and/or recently implanted joint replacements. * Implanted electric and electronic devices are a strict contraindication to magnetic resonance imaging, and in particular: heart pacemakers (especially older types), insulin pumps, implanted hearing aids, neuro-stimulators, intracranial metal clips, metallic bodies in the eye.

Design outcomes

Primary

MeasureTime frame
* Neurocognitive performance including the following domains: sustained, simple and complex attention, verbal and visual memory, executive function, verbal fluency, visuospatial skills, psychomotor speed, reaction time, reasoning, motor speed, working memory, processing speed and cognitive flexibility * Functional/structural connectivity within the DMN and SN

Secondary

MeasureTime frame
* Previous head injuries * Mental and neurologic health, e.g. Depression, ADHD, Anxiety, Migraine * QOL * Personal and sports career related variables, e.g. age, heading frequency, career length, playing position

Countries

The Netherlands

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP)