brain damage
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: two groups of atheltes will be included in this study:;50 football players - female, aged 30-50 years - played at least 5 mathces in a first league club team or the national team - retired from elite football over 2 years ago (no first league or international matches);30 elite athletes from non-contact sports - age, gender and handedness matched - former elite athlete (over 5 competitions at national or international level) in a non-contact sport or anthoer sport with a low risk of head injury - Retired from elite sports over 2 years ago (no competition on national or international level)
Exclusion criteria
Exclusion criteria: Football players * Previous non-football-related severe head injury diagnosed or treated by a physician * Symptomatic mental disorder (e.g. depression or schizophrenia). * Symptomatic chronic disease (i.e. cancer, diabetes, cardiovascular disease) except osteoarthrosis/-arthritis and medically controlled hypertension. * MRI contra-indications (specified below).;Elite athletes * Previous or current regular participation (* once a week for *1 year) in football, or other sports with high risk of head injury. * Previous severe head injury diagnosed or treated by a physician. * Symptomatic mental disorder (e.g. depression, schizophrenia). * Symptomatic chronic disease (i.e. cancer, diabetes, cardiovascular disease, dementia), except osteoarthrosis/-arthritis and medically controlled hypertension. * MRI contra-indications (specified below).;MRI Contraindication * Pregnancy (even though there is no evidence of adverse effects). * Metal and/or recently implanted joint replacements. * Implanted electric and electronic devices are a strict contraindication to magnetic resonance imaging, and in particular: heart pacemakers (especially older types), insulin pumps, implanted hearing aids, neuro-stimulators, intracranial metal clips, metallic bodies in the eye.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| * Neurocognitive performance including the following domains: sustained, simple and complex attention, verbal and visual memory, executive function, verbal fluency, visuospatial skills, psychomotor speed, reaction time, reasoning, motor speed, working memory, processing speed and cognitive flexibility * Functional/structural connectivity within the DMN and SN | — |
Secondary
| Measure | Time frame |
|---|---|
| * Previous head injuries * Mental and neurologic health, e.g. Depression, ADHD, Anxiety, Migraine * QOL * Personal and sports career related variables, e.g. age, heading frequency, career length, playing position | — |
Countries
The Netherlands