Unravelling the mechanism of azoospermia in nephropathic cystinosis

Unravelling the mechanism of azoospermia in nephropathic cystinosis - Azoospermia in nephropathic cystinosis

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON46648

Enrollment

Registered

2018-07-09

Start date

2018-10-01

Completion date

Unknown

Last updated

2024-04-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Nephropathic cystinosis

Interventions

None listed

Eligibility

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: Group A: male nephropatic cystinosis patients: - Post-pubertal, adult (> 18 years of age) males with infantile nephropathic cystinosis - Under cysteamine treatment Group B: control subjects with confirmed obstructive azoospermia - Patients with confirmed obstructive azoospermia - Ages: 18 - 45 years old Group C: healthy control subjects: - Healthy male donors - Ages: 18 - 45 years old

Exclusion criteria

Exclusion criteria: Group A: - Previous chemotherapy - (pre-/)pubertal boys - age below 18 years - unability to deliver consent due to mental disability Group B, C: - Previous chemotherapy - (Pre-/)pubertal boys - Age below 18 years - Underlying chronic disorder - Unability to deliver consent due to mental disability

Design outcomes

Primary

Measure	Time frame
Defining the origin of azoospermia in adult post-pubertal male infantile nephropathic cystinosis patients in terms of obstructive or non-obstructive azoospermia.	—

Countries

Netherlands

Outcome results