meniscus rupture meniscus tear
Conditions
Interventions
None listed
Sponsors
Leids Universitair Medisch Centrum
Eligibility
Age
18 Years to 99 Years
Inclusion criteria
Inclusion criteria: * 18 years or older; * Patients undergoing a total knee arthroplasty * No history of allergy to iodine, shellfish or ICG; * Not pregnant; * Absence of any psychological, familial sociological or geographical condition potentially hampering compliance with the study protocol and follow-up schedule; those conditions should be discussed with the patient before registration in the trial; * Before patient registration, written consent must be given according to ICH/GCP, national and local regulations.
Exclusion criteria
Exclusion criteria: - History of allergy to iodine, shellfish or ICG; - Hemodialyse - Patients with hyperthyroidism; - Pregnant or lactating woman; - Any condition that in the opinion of the investigator could potentially jeopardize the health status of the patient. - Patients with severe liver failure
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Visibility of meniscal vascularization | — |
Secondary
| Measure | Time frame |
|---|---|
| For the secondary objectives, the extent of the vascularization as determined based on NIR fluorescence intra-operative angiography (defined as mm from outer edge of meniscus) will be compared with the extent of the vascularization as determined based on histology (defined as mm from outer edge of meniscus). | — |
Countries
Netherlands
Outcome results
None listed