acute decompensated heart failure acute heart failure
Conditions
Interventions
None listed
Sponsors
Catharina-ziekenhuis
Eligibility
Age
18 Years to 99 Years
Inclusion criteria
Inclusion criteria: Undergo treatment for ADHF. Aged 18 or above and mentally competent. Capable of understanding the Dutch language.
Exclusion criteria
Exclusion criteria: Patients where follow-up is not possible (e.g. in-hospital mortality or follow-up not taking place at the Catharina Hospital).
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The main study parameters will be the ELAN-HF score, biomarker levels and clinical data that is collected during study inclusion. The main study endpoints are all-cause mortality and a composite of all-cause mortality and/or first readmission for cardiovascular reasons within 6 months after discharge. | — |
Secondary
| Measure | Time frame |
|---|---|
| Assess the associations between biomarker levels in patients admitted with ADHF and: - cause-specific mortality 6 months after discharge. - recurrent hospitalizations. - QoL outcomes early after discharge and 6 months after discharge. Develop a prognostic model that predicts QoL outcomes for patients that are admitted with acutely decompensated heart failure, based on serial measurements of a panel of biomarkers and clinical variables contained in electronic health records. Assess prognostic value of features extracted from continuous PPG and accelerometer data from the Elan device in patients that are discharged after they have been treated for ADHF. Assess agreement between a Hemodynamics model and the assessment of the degree of decompensation by the cardiologist. | — |
Countries
Netherlands
Outcome results
None listed