Improving Cognition in Severe Mental Illness: Cognitive Remediation Training combined with transcranial Direct Current Stimulation, a feasibility study.

Improving Cognition in Severe Mental Illness: Cognitive Remediation Training combined with transcranial Direct Current Stimulation, a feasibility study. - Improving cognition in SMI

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

NL-OMON

Registry ID

NL-OMON46594

Enrollment

Registered

2018-08-15

Start date

2018-03-01

Completion date

Unknown

Last updated

2024-04-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Psychiatric Disorders Severe Mental Illness

Interventions

During six weeks, service users will receive two sessions of cognitive remediation training per week, using either Circuits or Compensatory Cognitive Training. One training session will be combined

Eligibility

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: Service users can be included if they meet the criteria for Severe Mental Illness (Delespaul et al., 2013): - A psychiatric disorder that requires care/treatment (no symptomatic remission); - Severe disabilities in social and/or societal functioning (no functional remission); - Disabilities are the result of a psychiatric disorder - Disabilities are structural (at least several years); - Coordinated professional care is necessary to realize a treatment plan. ;Each participant in the study should sign informed consent, and only those who are fully capable of making their own decision regarding participation in the study will be included. Additional criteria for inclusion are an age between 18 to 55 and sufficient mastery of Dutch language.

Exclusion criteria

Exclusion criteria: • Metal implants inside the skull or eye; • Severe scalp skin lesions; • A history of previous seizures;

Design outcomes

Primary

Measure	Time frame
The primary outcome measure of this study is the feasibility of Circuits and Compensatory Cognitive Training for cognitive training in service users with severe mental illness and low levels of cognitive functioning. This will be measured using a self-designed feasibility assessment. The program that best meets our criteria for feasibility will be applied in a randomized controlled trial for the improvement of cognitive functioning in service users with SMI. For exploratory reasons only, an observational assessment for cognitive abilities is performed for each participant before and after the training period, to look at possible improvements in cognition.	—

Measure

Time frame

The primary outcome measure of this study is the feasibility of Circuits and Compensatory Cognitive Training for cognitive training in service users with severe mental illness and low levels of cognitive functioning. This will be measured using a self-designed feasibility assessment. The program that best meets our criteria for feasibility will be applied in a randomized controlled trial for the improvement of cognitive functioning in service users with SMI. For exploratory reasons only, an observational assessment for cognitive abilities is performed for each participant before and after the training period, to look at possible improvements in cognition.

—

Secondary

Measure	Time frame
none	—

Countries

Netherlands

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP)