lungcancer
Conditions
Interventions
None listed
Sponsors
Universiteit Twente
Eligibility
Age
18 Years to 99 Years
Inclusion criteria
Inclusion criteria: maximal 75 patients with a suspicion of lung cancer (in order to obtain 25 patients with lungcancer stage 3 / 4 and 25 patients with a negative diagnosis) - between 45-80 years of age
Exclusion criteria
Exclusion criteria: Patients; known other than lung cancer malignity, urinary tract infection Controls: known other than lung cancer malignity, no suspicion of lung cancer malignicy, pneumonia, urinary tract infection
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The main study parameters are microRNA sequencing data (read-counts per microRNA) derived from next generation sequencing of the small RNA fractions of blood and urine. The sequencing data will be correlated to clinical parameters: diagnosed with lung cancer (CT, histopathology), suspected of having lung cancer but not diagnosed (CT, possibly histopathology), not-suspected of lung cancer or any other disease. | — |
Secondary
| Measure | Time frame |
|---|---|
| Measurements of volatile organic compounds (VOCs) resulting from the electronic nose technology. With the primary outcomes and the secondary outcomes a predictive model will be developed to predict the probability for having lung cancer. | — |
Countries
Netherlands
Outcome results
None listed