Dit onderzoek heeft geen betrekking op een aandoening. not applicable
Conditions
Interventions
Participants will perform unilateral wrist flexion during which, through
virtual reality, different visual feedback conditions will be tested.
Sponsors
Vrije Universiteit
Eligibility
Age
18 Years to 99 Years
Inclusion criteria
Inclusion criteria: Healthy participants 18-65 years old Informed consent
Exclusion criteria
Exclusion criteria: (Family) history of epilepsy Neurological disorder Psychological disorder Use of (epileptogenic) medication Possessing a contraindication for single-pulse TMS (as determined by a TMS screening questionnaire: 'F1. Screening Questionnaire TMS safety') Either being directly involved in the study, an employee at the research department or a family member of staff of the research department.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The primary outcome measures of the study described by the amendment are the amplitude of the motor evoked potentials, representative of corticospinal excitability, and the degree of suppression of the EMG signal during an 'ipsilateral silent period', representative for interhemispheric inhibition. Within a repeated measures design, differences in these measures will be tested across visual feedback conditions. | — |
Secondary
| Measure | Time frame |
|---|---|
| Relative phase of the left flexing hand with respect to the right virtual hand will be used as a measure of task performance. Depending on the specific research questions, described in subsequent amendments, other secondary measures might be included. For the current protocol these are not applicable. | — |
Countries
Netherlands
Outcome results
None listed