Fragile X Syndrome FXS
Conditions
Interventions
Autism Spectrum Disorder
Cognition
Developmental Delay
Fragile X Syndrome
Sponsors
Erasmus MC, Universitair Medisch Centrum Rotterdam
Eligibility
Age
2 Years to 64 Years
Inclusion criteria
Inclusion criteria: Children aged 6-18 years, (corrected to) normal vision, Dutch as first language. Four groups of 55 participants are included. Two groups of mothers (n
Exclusion criteria
Exclusion criteria: Four groups of participants are included. Group specific in- and exclusion criteria are provided in section 4.2 and 4.3 of the research protocol.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| For the three domains, the main study parameters are: - ASD severity: ASD severity scores from structured behavioral observations. - cognitive abilities: IQ, measured using an age-appropriate IQ test. - (neuro)biological characteristics: brain activation patterns measured using fNIRS. | — |
Secondary
| Measure | Time frame |
|---|---|
| Our secondary parameters will be: Biological measures (i.e. eye-movements and FMRP levels; see section 8.3 for an extensive description of all assessments and outcomes). | — |
Countries
The Netherlands
Outcome results
None listed