fitheid performance physical fitness
Conditions
Interventions
In this crossover study, participants will daily receive either a placebo or
Actiful®, a supplement containing 500 mg orange extract and 200 mg pomegranate
actives, for 4 weeks followed by a wash-ou
Sponsors
Bioactor BV
Eligibility
Age
18 Years to 99 Years
Inclusion criteria
Inclusion criteria: Healthy male/female (based on medical history provided during a general health questionnaire); Age between 60 * 75
Exclusion criteria
Exclusion criteria: - Allergy to test product/placebo - Allergy to citrus fruits - BMI lower than 18 or higher than 28 - Recent muscle injury in less than one month before the start of the study. - Medical conditions that might influence outcome measure or participant safety during testing, including but not limited to: severe cardiovascular disease, cancer, Parkinson*s disease. To be decided by PI. - High blood pressure (systolic * 140 mmHg, diastolic * 90 mmHg (40) - Use of medication that may interfere with the study results - Smoking - Administration of investigational drugs or participation in any scientific intervention study which may interfere with this study (to be decided by the principle investigator), in the 180 days prior to the study. - Abuse of products; alcohol (> 20 alcoholic units per week) and drugs. - Unable to correctly perform the tests during the familiarization test
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Main endpoints are distance covered during a 6 minute walk test (6 MWT) | — |
Secondary
| Measure | Time frame |
|---|---|
| Secondary endpoints include the quality of life, as measured by the WHOQOL-BREF questionnaire, lower body strength as measured by the 30s chair stand test, upper body strenght as measured by an arm curl test, lower body flexibility as measured by a chair sit and reach test, upper body flexibility as measured by a back scatch test, heart rate (HR) in rest and during a 6 minute walk test, daily physical activity measured with accelerometer, and blood parameters of antioxidative capacity and inflammation. | — |
Countries
Netherlands
Outcome results
None listed