kidney failure
Conditions
Interventions
None listed
Sponsors
Pathologie
Eligibility
Age
18 Years to 99 Years
Inclusion criteria
Inclusion criteria: Patients who undergo a nephrectomy for a suspected renal cell carcinoma and who are 18 years or older and are able to read and write.
Exclusion criteria
Exclusion criteria: none
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Primary Objective: The primary objective of the study is to assess the relationship between renal PTC density and renal function before and two years after surgery. | — |
Secondary
| Measure | Time frame |
|---|---|
| Secondary Objectives: The secondary objectives of the study are to assess a) the relationship between renal PTC density and systemic capillary density and microvascular function in patients with and without CKD at nephrectomy and after two years. b) the relationship between renal PTC density and histological and molecular damage (e.g. IF/TA, inflammation, angiogenic profiling, MSI) in renal tissue in patients with and without CKD at nephrectomy and after two years. c) the relationship between renal PTC density and renal function in relation to known cardiovascular risk factors such as demographic variables (age, gender), clinical variables (renal function, hypertension. glucose intolerance, mineral metabolism, BMI), and medical history (smoking history, medication use, birth weight). | — |
Countries
Netherlands
Outcome results
None listed