inventeristie mogelijkheid van virusoverdracht van vleermuis naar mens infectious diseases zoonosis
Conditions
Interventions
None listed
Sponsors
Universitair Medisch Centrum
Eligibility
Age
18 Years to 99 Years
Inclusion criteria
Inclusion criteria: (regular) contact with bats
Exclusion criteria
Exclusion criteria: none
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| We will develop serological assays that detect exposure to identified bat viruses. We will test 300 human sera. With this quantity we can detect an antibody prevalence of over 1%, at the 95% confidence interval. The results will support assessments on the needs for and the development of preventive interventions against virus transmission from bats to humans. | — |
Secondary
| Measure | Time frame |
|---|---|
| - Reported level of bat contact (data coming from the questionnaire) and presence of antibodies against bat viruses (data coming from serology study) will be related to each other, to profession, ethnical background, gender and age, to identify possible risk factors. This will only be possible if statistically sound, which depends on the results of the questionnaire and serology study. - potentially, clinical signs after contact with a bat, and relatedness of the clinical signs to seroconversion in the volunteer | — |
Countries
Netherlands
Outcome results
None listed