Predicting treatment success in anxiety disorder patients by use of biomarkers

Predicting treatment success in anxiety disorder patients by use of biomarkers - Predictive biomarkers for treatment of anxiety

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON46417

Enrollment

Registered

2018-07-12

Start date

2019-04-05

Completion date

Unknown

Last updated

2024-04-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

anxiety

Interventions

None listed

Eligibility

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: diagnose of anxiety disorder enrollment at intensive exposure therapy program at Pro Persona/Onderwaal Nijmegen cognitive competent, 18-65 years fMRI compatibility

Exclusion criteria

Exclusion criteria: History of or current or previous neurological disorders, psychosis or delusional disorders History of current brain surgery or epilepsy Pregnancy Metal parts in the upper body, implants, medical devices or medicinal plasters Claustrophobia

Design outcomes

Primary

Measure	Time frame
In the fMR session three paradigms will be tested to determine the neural phenotype: prefrontal regulation task salience processing task face processing task Therapy evaluation: A therapy evaluation is routinly in place at pro Persona including a questionnaire battery. We will analyze the aquestionnaire data regarding the therapy outcome and relate results to previously determined neural mechanisms in the individual patient.	—

Measure

Time frame

In the fMR session three paradigms will be tested to determine the neural phenotype: prefrontal regulation task salience processing task face processing task Therapy evaluation: A therapy evaluation is routinly in place at pro Persona including a questionnaire battery. We will analyze the aquestionnaire data regarding the therapy outcome and relate results to previously determined neural mechanisms in the individual patient.

—

Secondary

Measure	Time frame
questionnaires: FEELE (Emotional Adjustment Questionnaire for Adults, Grob & Horowitz, 2014) Biological markers for stress: heart rate skin conductance pupil dilation shoulder muscle tension (MEG)	—

Countries

Netherlands

Outcome results