Differences in response of hemodynamic parameters between pregnant and non-pregnant women during a cardiopulmonary exercise test.

Differences in response of hemodynamic parameters between pregnant and non-pregnant women during a cardiopulmonary exercise test. - Hemodynamic response in pregnancy.

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON46409

Enrollment

Registered

2018-05-16

Start date

2018-05-24

Completion date

Unknown

Last updated

2024-04-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Pregnancy

Interventions

None listed

Eligibility

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: - 20 pregnant women,

Exclusion criteria

Exclusion criteria: - Any known pre-existing cardiovascular, respiratory, hypertensive or systemic disorder - Orthopaedic impairment that compromises exercise performance - History of placenta-related pregnancy complications (PPC) - Multiple pregnancy - Smoking or quit smoking

Design outcomes

Primary

Measure	Time frame
Differences in response of cardiac output (*CO) during a CPET, measured with ICG (by Physioflow), between pregnant and non-pregnant women.	—

Secondary

Measure	Time frame
Differences in (response of) hemodynamic parameters, ventilation parameters and aerobic capacity during and after a CPET (measured with ICG, breath-by-breath analysis, a finger prick blood sampling and a pulse oximeter) between pregnant women and non-pregnant women. The parameters that will be measured or calculated are: - Heart rate - Blood pressure - Stroke volume - Left cardiac function - Systemic vascular resistance - Velocity index - Sensitivity index submaximal (VO2 / stroke volume index) - Oxygen saturation - Gas exchange (VO2 and VCO2) - PetCO2 (End Tidal CO2) - EqCO2 (Equivalent CO2) - Anaerobic treshold - Lactate level in capillary blood	—

Measure

Time frame

Differences in (response of) hemodynamic parameters, ventilation parameters and aerobic capacity during and after a CPET (measured with ICG, breath-by-breath analysis, a finger prick blood sampling and a pulse oximeter) between pregnant women and non-pregnant women. The parameters that will be measured or calculated are: - Heart rate - Blood pressure - Stroke volume - Left cardiac function - Systemic vascular resistance - Velocity index - Sensitivity index submaximal (VO2 / stroke volume index) - Oxygen saturation - Gas exchange (VO2 and VCO2) - PetCO2 (End Tidal CO2) - EqCO2 (Equivalent CO2) - Anaerobic treshold - Lactate level in capillary blood

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Countries

Netherlands

Outcome results