recurrence of atrial fibrillation
Conditions
Interventions
None listed
Sponsors
Onze Lieve Vrouwe Gasthuis
Eligibility
Age
18 Years to 99 Years
Inclusion criteria
Inclusion criteria: (i) Index pulmonary veins isolation between 2012-2017 (ii) second generation cryo ballon used during pulmonary vein ablation (iii) persistent atrial fibrillation (>7 days,
Exclusion criteria
Exclusion criteria: (i) Any left atrium ablation prior to index pulmonary veins isolation (ii) additional ablation lines, except cavotricuspid isthmus line (iii) unwilling/ uncapable to provide informed consent for long term follow up.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Freedom of recurrence of atrial fibrillation (>30sec documented on ECG, Holter or CIED). Recurrence of AF will be categorized in paroxysmal (if less than 7days), persistent (if between 7days- 1 year) or longstanding persistent (if less than 1year). The occurrence will be categorized in four groups, one or less AF episode a year, 2-3 AF episodes a year, more than 3 AF episodes a year or permanent AF. | — |
Secondary
| Measure | Time frame |
|---|---|
| - Use of anti arrhythmic drugs during the follow up period. - Freedom of recurrence of any atrial arrhythmia (>30sec documented on ECG, Holter or CIED). - Quality of life (AFEQT questionnaire). - Symptoms of palpitations after ablation - Acute procedural success - Early complications: - Groin vascular complication, - Transient phrenic nerve palsy, - Pericardial effusion. - Procedural stroke - Late complications: - Persistent phrenic nerve palsy, - Venous thrombosis, - 30 days mortality. - Procedural characteristics; procedure time, fluoroscopic time, total ablation time, total amount of applications. - Cryo characteristics; pulmonary veins failed to isolate, average temperature during application. | — |
Countries
Netherlands
Outcome results
None listed