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Open- and closed-label nocebo and placebo verbal suggestions regarding a sham transdermal patch: effects on itch

Open- and closed-label nocebo and placebo verbal suggestions regarding a sham transdermal patch: effects on itch - Open- and closed-label suggestions and itch

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
NL-OMON
Registry ID
NL-OMON46396
Enrollment
112
Registered
2018-04-05
Start date
2018-04-12
Completion date
Unknown
Last updated
2024-06-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Het onderzoek wordt bij gezonde proefpersonen uitgevoerd. Uitkomsten uit deze lijn van onderzoek bieden nieuwe handvatten voor verklaringsmodellen en therapeutische interventies voor aandoeningen waarbij jeuk een symptoom is. Not applicable

Interventions

Sponsors

Universiteit Leiden
Lead Sponsor

Eligibility

Age
18 Years to 99 Years

Inclusion criteria

Inclusion criteria: Between 18 and 35 years old; good understanding of written and spoken Dutch

Exclusion criteria

Exclusion criteria: Refusal to give written informed consent; severe somatic or psychological morbidity (e.g., heart and lung diseases or DSM-IV psychiatric disorders) that would adversely affect participant*s safety or that might interfere with the study protocol; current chronic itch or pain complaints; current use of analgesics, anti-inflammatory drugs, antihistamines, or antibiotics; recent vaccinations; pregnancy; colour blindness

Design outcomes

Primary

MeasureTime frame
The main study parameter is self-reported itch in response to histamine iontophoresis.

Secondary

MeasureTime frame
Secondary study parameters include expectations, self-reported and physical skin condition, and wellbeing (e.g., anxiety). In addition, effects of personality factors on expectation induction and study outcomes will be explored. Effects on response time on the Stroop test and Trail Making Test will be explored as well.

Countries

Netherlands

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP)