Het onderzoek wordt bij gezonde proefpersonen uitgevoerd. Uitkomsten uit deze lijn van onderzoek bieden nieuwe handvatten voor verklaringsmodellen en therapeutische interventies voor aandoeningen waarbij jeuk een symptoom is. Not applicable
Conditions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: Between 18 and 35 years old; good understanding of written and spoken Dutch
Exclusion criteria
Exclusion criteria: Refusal to give written informed consent; severe somatic or psychological morbidity (e.g., heart and lung diseases or DSM-IV psychiatric disorders) that would adversely affect participant*s safety or that might interfere with the study protocol; current chronic itch or pain complaints; current use of analgesics, anti-inflammatory drugs, antihistamines, or antibiotics; recent vaccinations; pregnancy; colour blindness
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The main study parameter is self-reported itch in response to histamine iontophoresis. | — |
Secondary
| Measure | Time frame |
|---|---|
| Secondary study parameters include expectations, self-reported and physical skin condition, and wellbeing (e.g., anxiety). In addition, effects of personality factors on expectation induction and study outcomes will be explored. Effects on response time on the Stroop test and Trail Making Test will be explored as well. | — |
Countries
Netherlands