Treating the compromised hearts of patients with Rheumatoid Arthritis * Can we repair the damage?

Treating the compromised hearts of patients with Rheumatoid Arthritis * Can we repair the damage? - Heart failure in RA

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON46382

Enrollment

Registered

2018-02-14

Start date

2018-01-01

Completion date

Unknown

Last updated

2025-03-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

diastolic heartfailure Heart failure with preserved ejection fraction (HFrEF)

Interventions

None listed

Eligibility

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: Diagnosis of: o RA, according to the ARC/EULAR 2010 criteria (11) - Active disease: DAS28*3.2 AND C-reactive protein >10 mg/l OR erythrocyte sedimentation rate (ESR) >15mm/h - Minimal knee bending/flexion angle of 90 degrees of both knees. - Age 40-70 years

Exclusion criteria

Exclusion criteria: -medical history of ischemic heart disease of congestive heart failure NYHA class III/IV

Design outcomes

Primary

Measure	Time frame
Diastolic dysfunction based on the 2016 ESC guidelines.(Naguah et al, J Am Soc Echocardiogr. 2016 Apr;29(4):277-314.) Disease activity: described as DAS28, blood inflammation parameters (CRP, BSE, IL-6, TNF, leucocytes), HAQ and SF36.	—

Secondary

Measure	Time frame
Systolic dysfunction: Systolic dysfunction will be defined as an ejection fraction of	—

Countries

Netherlands

Outcome results