metabolic disease mitochondrial diseases oxidative phosporylation diseases
Conditions
Interventions
Participants will receive blended cognitive behavioral therapy (CBT) for
fatigue in addition to care as usual. The PowerMe intervention covers a period
of 4 months in which the patient will have 8 m
Sponsors
Radboud Universitair Medisch Centrum
Eligibility
Age
2 Years to 17 Years
Inclusion criteria
Inclusion criteria: - Age between 8 and 18 years - Able to speak, write, and read Dutch - Diagnosed with genetically confirmed mitochondrial disease - Being severely fatigued (CIS fatigue >= 35) - Access to a computer with internet connection - Basic computer skills - Able to travel to the Radboudumc for the CBT intervention (3 visits)
Exclusion criteria
Exclusion criteria: - Intellectual disability (developmental age younger than 8 years). - Primary depression (CDI >=16) or anxiety disorder (SCARED-C >= 25) - No current psychological treatment for fatigue
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The primary outcome is perceived fatigue. | — |
Secondary
| Measure | Time frame |
|---|---|
| Secondary outcomes in children with mitochondrial disease are quality of life, physical functioning and school attendance. | — |
Countries
Netherlands
Outcome results
None listed