Fysiologie Difference in gastric behavior between human milk and infant formula
Conditions
Interventions
Each participant will drink 200 mL of her own breastmilk or, in another
session, commercial infant formula. Gastric content will be monitored using
magnetic resonance imaging (MRI). MRI scans will b
Sponsors
Wageningen Universiteit
Eligibility
Age
18 Years to 99 Years
Inclusion criteria
Inclusion criteria: Female Lactating Given birth at least 4 weeks ago Given birth to a single child, no twins Being healthy (self-reported) Non-smoking Having given written informed consent Need to be willing to receive information about incidental findings of pathology
Exclusion criteria
Exclusion criteria: Lactating for more than 1 year Bovine milk allergy or intolerance (self-reported) Lactose intolerance (self-reported) Gastric disorders or regular gastric complaints, heart burn for example Use of proton pump inhibitors or other medication which alters the normal functioning of the stomach Smoking Inability to comfortably produce an additional 225 mL of milk Having a contra-indication to MRI scanning
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Gastric content in mL over time and half gastric emptying time (t50) mL of the individual layers within the stomach and the time when they are observed. | — |
Secondary
| Measure | Time frame |
|---|---|
| The participants will be asked to rate their sense of fullness, bloating and nausea from 0 to a 100. | — |
Countries
Netherlands
Outcome results
None listed