breast cancer breast carcinoma
Conditions
Interventions
The intervention will be performed under sterile conditions and, if needed,
with local anesthesia of the skin using lidocaine 1% (max 5cc). 2-4 ml of
Iodined PolyEthyleneGlycol, brandname *TraceIT*
Sponsors
Sint Franciscus Gasthuis
Eligibility
Age
18 Years to 99 Years
Inclusion criteria
Inclusion criteria: Women following breast conserving surgery for breast cancer and/or ductal carcinoma in situ (DCIS) with an indication for boost or partial breast radiotherapy according to local protocol of the Erasmus MC. CVS score 1-3 on original CT-planning for radiotherapy. written informed consent
Exclusion criteria
Exclusion criteria: Oncoplastic technique (level 2: volume replacement) performed Patients with known allergies for PEG or Iodine No surgical scar visible / post-operative effects visible on US
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Primary endpoint: the Conformity Index (Cx) of target definition. | — |
Secondary
| Measure | Time frame |
|---|---|
| Secondary endpoints: the distance between observers* target volumes (dCOM), target volumes, Cavity Visualisation Score, feasibility of the hydrogel marker injection, stability of the hydrogel marker volume over time, adverse events, ease of use, motion of hydrogel marker/clips over time, feasibility of using the hydrogel for patient positioning and comparison of dose to organs at risk for treatment plans with and without hydrogel. | — |
Countries
Netherlands
Outcome results
None listed